Fig. 1 · Structure

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5'-O-DMT-rU

Modified Nucleoside

5'-O-DMT-rU is a modified nucleoside that serves as a crucial building block for RNA synthesis. Its protective 5'-O-dimethoxytrityl (DMT) group facilitates the efficient incorporation of ribouridine into RNA strands. This reagent is widely utilized in the development of oligonucleotides for various applications, including gene expression studies, RNA interference, and the development of ribozymes.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 81246-79-9
Applications Modified Nucleoside
Formula C30H30N2O8
Molecular Weight 546.57
SMILES
O[C@@H]([C@@H](O)[C@H](N1C(NC(C=C1)=O)=O)O2)[C@H]2COC(C3=CC=C(OC)C=C3)(C4=CC=CC=C4)C5=CC=C(OC)C=C5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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