Fig. 1 · Structure
Documents & Downloads
5-PA-dUTP
Nucleotide
5-PA-dUTP (5-Propargylamino-dUTP) is a C5-modified nucleotide that features an alkyne group, enabling its application in click chemistry. It can be incorporated into DNA nanoparticles for efficient delivery of photosensitizers. Additionally, 5-PA-dUTP can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc), making it a valuable reagent for molecular conjugation and bioconjugation studies. This compound is useful in various research applications, including gene therapy and the development of targeted delivery systems.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 179101-49-6 |
| Applications | Nucleotide |
| Formula | C12H18N3O14P3 |
| Molecular Weight | 521.20 |
| Synonyms | 5-Propargylamino-dUTP |
| SMILES | O=C1N([C@H]2C[C@H](O)[C@@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)O2)C=C(C(N1)=O)C#CCN |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.