Fig. 1 · Structure
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5-PT formic
Serotonin Derivative
5-PT formic is an alkyne-functionalized derivative of serotonin (5-HT) that serves as a serotonylation substrate in living cells. This compound facilitates the identification of serotonylated proteins through conjugation with biotin, employing copper-click chemistry and mass spectrometry techniques. Additionally, 5-PT formic is effective in labeling and isolating serotonylated cells, particularly in alveolar epithelial cells, making it a valuable tool for proteomic analysis. Its applications extend to research in bronchopulmonary dysplasia, enhancing the understanding of this condition at the molecular level.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Substrate |
| CAS Number | 2906227-87-8 |
| Applications | Serotonin Derivative |
| Formula | C14H16N2O3 |
| Molecular Weight | 260.29 |
| Synonyms | 5-Propargyltryptamide formic |
| SMILES | NCCC1=CNC2=C1C=C(OCC#C)C=C2.OC=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.