Fig. 1 · Structure

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5-PT

5-HT Derivative

5-Propargyltryptamide (5-PT) is an alkyne-functionalized derivative of serotonin (5-HT), serving as a substrate for serotonylation in living cells. This reagent enables the conjugation of biotin, facilitating the identification of serotonylated proteins through copper-catalyzed click chemistry and mass spectrometry. 5-PT selectively labels and isolates serotonylated proteins in alveolar epithelial cells, making it a valuable tool for proteomic analysis in the study of bronchopulmonary dysplasia and related respiratory conditions.

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Specifications

Manufacturer Adooq Bioscience
Actions Substrate
CAS Number 92085-05-7
Applications 5-HT Derivative
Formula C13H14N2O
Molecular Weight 214.26
Synonyms 5-Propargyltryptamide
SMILES
NCCC1=CNC2=C1C=C(OCC#C)C=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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