Fig. 1 · Structure
Documents & Downloads
5-Vinyl-2'-deoxyuridine (5-VdU)
DNA Damage Agent
5-Vinyl-2'-deoxyuridine is a thymidine analogue that acts as a DNA damage agent, incorporated into cellular DNA during replication. As a click chemistry reagent due to the presence of an alkyne group, it facilitates targeted modifications and can induce DNA damage, ultimately leading to apoptosis in human cultured cells. This compound is useful for research applications focusing on DNA repair mechanisms, cell cycle regulation, and apoptosis pathways.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 55520-67-7 |
| Applications | DNA Damage Agent |
| Formula | C11H14N2O5 |
| Molecular Weight | 254.24 |
| Synonyms | 5-VINYL-DURD; 5-VdU |
| SMILES | O[C@H]1C[C@H](N2C(NC(C(C=C)=C2)=O)=O)O[C@@H]1CO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.