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503O8,12

Ionizable Cationic Lipidoid

503O8,12 is an ionizable cationic lipidoid designed for efficient mRNA delivery, particularly targeting the spleen and lungs in murine models when combined with neutral helper lipid DOPE in lipid nanoparticles. Its unique formulation enhances the stability and bioavailability of mRNA, facilitating transfection in various research applications, including vaccine development and gene therapy.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	3067564-98-8
Applications	Ionizable Cationic Lipidoid
Formula	C₁₀₁H₂₀₀N₄O₈
Molecular Weight	1598.69
SMILES	O=C(CCN(CCN(CCCN(CCN(CCC(OCC(CCCCCCCCCC)CCCCCCCC)=O)CCC(OCC(CCCCCCCCCC)CCCCCCCC)=O)C)C)CCC(OCC(CCCCCCCCCC)CCCCCCCC)=O)OCC(CCCCCCCCCC)CCCCCCCC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.