Fig. 1 · Structure
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5α-Androstan-3β-ol
CAR Inverse Agonist Ligand
5α-Androstan-3β-ol acts as an inverse agonist ligand for the constitutive androstane receptor (CAR). This saturated sterol modulates CAR activity, influencing various biological pathways associated with xenobiotic metabolism. Its ability to increase AmB-channel conductance in a concentration-dependent manner makes it a valuable tool for studies in pharmacology and toxicology research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inverse Agonist |
| CAS Number | 1224-92-6 |
| Applications | CAR Inverse Agonist Ligand |
| Formula | C19H32O |
| Molecular Weight | 276.46 |
| Synonyms | 3β-Hydroxy-5α-androstane |
| SMILES | C[C@@]12[C@]3([H])[C@](CC[C@@]1([H])C[C@H](CC2)O)([H])[C@@]4([H])[C@](CC3)(CCC4)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.