Fig. 1 · Structure

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5A2-SC8

Lipid-Like Compound

5A2-SC8 is an ionizable amino lipid designed for incorporation in lipid nanoparticles (LNPs) that facilitate the efficient delivery of small RNAs, including siRNA and miRNA, into tumor cells. This compound demonstrates a favorable safety profile in vivo, minimizing toxicity while enhancing therapeutic efficacy. Its unique mechanism of action allows for specific delivery within the liver, potentially improving treatment outcomes in cancer research applications.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1857341-90-2
Applications Lipid-Like Compound
Formula C93H173N5O20S5
Molecular Weight 1841.72
SMILES
O=C(CCN(CCNCCN(CCC(OCCOC(C(CSCCCCCCCC)C)=O)=O)CCC(OCCOC(C(CSCCCCCCCC)C)=O)=O)CCNCCN(CCC(OCCOC(C(CSCCCCCCCC)C)=O)=O)CCC(OCCOC(C(CSCCCCCCCC)C)=O)=O)OCCOC(C(CSCCCCCCCC)C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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