5β,6β-epoxycholestanol is an oxidative metabolite of cholesterol that targets cellular oxidative stress pathways. It has been shown to induce lactate dehydrogenase (LDH) release and promote apoptosis in macrophage-differentiated U937 cells. This compound is particularly relevant in studies of atherosclerosis, as it has been identified in human fatty streaks and advanced atherosclerotic lesions, providing insight into cholesterol metabolism and its implications in cardiovascular disease.
5β,6β-epoxycholestanol is an oxidative metabolite of cholesterol that targets cellular oxidative stress pathways. It has been shown to induce lactate dehydrogenase (LDH) release and promote apoptosis in macrophage-differentiated U937 cells. This compound is particularly relevant in studies of atherosclerosis, as it has been identified in human fatty streaks and advanced atherosclerotic lesions, providing insight into cholesterol metabolism and its implications in cardiovascular disease.
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