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6,7-Dehydro Norethindrone

Norethisterone Metabolite

6,7-Dehydro Norethindrone, a metabolite of Norethisterone, primarily targets p53, a critical regulator of the cell cycle. This compound is produced through the biotransformation of Norethisterone by Rhizopus microsporus PT2906. It has been shown to induce apoptosis and inhibit the degradation of p53, displaying selective antitumor activity against cervical cancer. These properties make 6,7-Dehydro Norethindrone a valuable reagent for cancer research and studies focused on apoptosis mechanisms.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	31528-46-8
Applications	Norethisterone Metabolite
Formula	C₂₀H₂₄O₂
Molecular Weight	296.40
Synonyms	6,7-Didehydronorethisterone
SMILES	O[C@@]1(C#C)CC[C@@]2([H])[C@]3([H])C=CC4=CC(CC[C@]4([H])[C@@]3([H])CC[C@]12C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.