Fig. 1 · Structure
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6-Aminophenanthridine
PFAR Inhibitor
6-Aminophenanthridine is an inhibitor of the protein folding activity of the ribosome, specifically targeting the PFAR complex. This compound functions by competitively occluding protein substrates from binding to ribosomal RNA (rRNA), ultimately leading to the inhibition of PFAR activity. It is valuable for research applications focused on protein synthesis, ribosome function, and cellular stress responses.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 832-68-8 |
| Applications | PFAR Inhibitor |
| Formula | C13H10N2 |
| Molecular Weight | 194.23 |
| SMILES | NC1=C2C=CC=CC2=C(C=CC=C3)C3=N1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.