Fig. 1 · Structure

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6-Chloroindole-2-carboxylic acid

Ns4a-Ns3p Binder

6-Chloroindole-2-carboxylic acid is a specific binder of the NS4A-NS3P protein complex, targeting the hepatitis C virus NS3 protease. This compound demonstrates significant affinity, with a KD value of 0.4 mM, highlighting its potential utility in antiviral research and drug development. Its properties make it a valuable reagent for studying hepatitis C virus mechanisms and developing therapeutic strategies.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 16732-75-5
Applications Ns4a-Ns3p Binder
Formula C9H6ClNO2
Molecular Weight 195.60
SMILES
O=C(O)C1=CC=2C=CC(Cl)=CC2N1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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