Fig. 1 · Structure
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6-Ethyl-7-hydroxy-4-methyl-2H-chromen-2-one
Mcl-1 Inhibitor
6-Ethyl-7-hydroxy-4-methyl-2H-chromen-2-one functions as a selective Mcl-1 inhibitor, exhibiting a Ki value of 5.47 μM and an IC50 of 30.88 μM. This compound is relevant for studies focused on apoptosis regulation in cancer research, providing insights into therapeutic strategies targeting Mcl-1 mediated pathways. It may facilitate investigations into the mechanisms of cell survival and death, contributing to the development of novel anticancer therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1484-73-7 |
| Applications | Mcl-1 Inhibitor |
| Formula | C12H12O3 |
| Molecular Weight | 204.23 |
| SMILES | O=C1OC=2C=C(O)C(=CC2C(=C1)C)CC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.