Fig. 1 · Structure
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6-Fluorotryptophan
Tryptophan Hydroxylase Inhibitor
6-Fluorotryptophan is a competitive inhibitor of tryptophan hydroxylase, an enzyme crucial for serotonin synthesis. This compound has demonstrated significant effects on sleep disruption in animal models, particularly in rats with chronic EEG electrode implantation. Its application in research includes studies on serotonin-related disorders and the modulation of sleep patterns, providing insights into the neurochemical mechanisms underlying these processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 7730-20-3 |
| Applications | Tryptophan Hydroxylase Inhibitor |
| Formula | C11H11FN2O2 |
| Molecular Weight | 222.22 |
| SMILES | NC(CC1=CNC2=C1C=CC(F)=C2)C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.