6-Hydroxy-2,2′,4,4′-tetrabromodiphenyl ether is a selective inhibitor of Tie2 kinase, exhibiting an IC50 value of 2.1 μM. This compound interacts with the ATP binding site of Tie2, effectively inhibiting its kinase activity and thereby blocking tumor angiogenesis. It is a valuable tool for research focused on vascular biology and cancer therapeutics.
6-Hydroxy-2,2′,4,4′-tetrabromodiphenyl ether is a selective inhibitor of Tie2 kinase, exhibiting an IC50 value of 2.1 μM. This compound interacts with the ATP binding site of Tie2, effectively inhibiting its kinase activity and thereby blocking tumor angiogenesis. It is a valuable tool for research focused on vascular biology and cancer therapeutics.
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