Fig. 1 · Structure
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6-Hydroxy bexarotene
Metabolites
6-Hydroxy bexarotene is the primary circulating metabolite of the retinoid compound bexarotene, identified in various species including rats, dogs, and humans. This metabolite demonstrates a markedly lower affinity for retinoid receptors compared to its parent compound and exhibits minimal activity in activating retinoic acid receptors. It serves as an important tool for understanding the pharmacokinetics and biological effects of bexarotene in research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 368451-07-4 |
| Applications | Metabolites |
| Formula | C24H28O3 |
| Molecular Weight | 364.48 |
| SMILES | CC1=CC2=C(C(C)(CC(C2(C)C)O)C)C=C1C(C3=CC=C(C=C3)C(O)=O)=C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.