Fig. 1 · Structure
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6-Hydroxybenzbromarone
Benzbromarone Metabolite
6-Hydroxybenzbromarone is a key metabolite of Benzbromarone, exhibiting enhanced pharmacological potency and a longer half-life. This compound functions as an inhibitor of the protein Eyes Absent 3 (EYA3), with an IC50 of 21.5 μM. Its anti-angiogenic properties are evidenced by its ability to inhibit cell migration, tubulogenesis, and angiogenic sprouting, making it a valuable reagent for research in cancer biology and vascular development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 152831-00-0 |
| Applications | Benzbromarone Metabolite |
| Formula | C17H12Br2O4 |
| Molecular Weight | 440.08 |
| SMILES | O=C(C1=CC(Br)=C(O)C(Br)=C1)C2=C(CC)OC3=CC(O)=CC=C23 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.