Fig. 1 · Structure
Documents & Downloads
6-Hydroxykynurenic acid
kynurenic acid Derivative
6-Hydroxykynurenic acid (6-HKA) is a derivative of kynurenic acid (KYNA) that acts as a low-affinity antagonist of the N-methyl-D-aspartate receptor (NMDAR), with an IC50 of 59 μM. This compound has been studied for its potential roles in neuroprotective and neuropsychiatric research, including its effects on glutamate signaling pathways. Its unique properties make it a valuable tool for elucidating the mechanisms underlying various neurological conditions.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 3778-29-8 |
| Applications | kynurenic acid Derivative |
| Formula | C10H7NO4 |
| Molecular Weight | 205.17 |
| Synonyms | 6-HKA |
| SMILES | O=C(C1=CC(O)=C2C=C(O)C=CC2=N1)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.