Fig. 1 · Structure

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6-O-Isobutyrylbritannilactone

Melanogenesis Inhibitor

6-O-Isobutyrylbritannilactone is a natural melanogenesis inhibitor derived from the flowers of Inula britannica. This sesquiterpene effectively inhibits IBMX-induced melanin production in B16F10 melanoma cells. Additionally, 6-O-Isobutyrylbritannilactone modulates key signaling pathways, including ERK, PI3K/AKT, and CREB, demonstrating significant antimelanogenic activity in zebrafish embryo models. Its properties make it a valuable reagent for research focused on pigment biology and skin disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1259933-02-2
Applications Melanogenesis Inhibitor
Formula C19H28O5
Molecular Weight 336.42
SMILES
CC(C)C(O[C@H]1[C@@]2([H])[C@@](OC(C2=C)=O)([H])CC(C)=C1[C@@H](C)CCCO)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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