Fig. 1 · Structure

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6-PhEt-dATP

ATP Analog

6-PhEt-dATP is an ATP analog that selectively enhances the activity of specific cystic fibrosis transmembrane conductance regulator (CFTR) mutants. This reagent is valuable for investigating the biochemical mechanisms underlying cystic fibrosis and for evaluating potential therapeutic strategies targeting these mutant forms of CFTR. Researchers can utilize 6-PhEt-dATP to assess the functionality of CFTR in cellular models and to explore drug responses in cystic fibrosis research.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1239610-11-7
Applications ATP Analog
Formula C18H24N5O12P3
Molecular Weight 595.33
SMILES
O[C@H]1C[C@H](N(C=N2)C3=C2C(NCCC4=CC=CC=C4)=NC=N3)O[C@@H]1COP(OP(OP(O)(O)=O)(O)=O)(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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