Fig. 1 · Structure
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6-Phosphoglucono-δ-lactone
G6PD Reversal Substrate
6-Phosphoglucono-δ-lactone acts as a reversal substrate for glucose-6-phosphate dehydrogenase (G6PD). This compound serves as an intermediate in the oxidative branch of the pentose phosphate pathway (PPP), generated from D-glucose-6-phosphate by G6PDH and subsequently converted to 6-phosphoglutonate by lactonase. 6-Phosphoglucono-δ-lactone is valuable in research focused on heart failure, type 2 diabetes, and various cancer studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Substrate |
| CAS Number | 2641-81-8 |
| Applications | G6PD Reversal Substrate |
| Formula | C6H11O9P |
| Molecular Weight | 258.12 |
| Synonyms | 6-PGδL; 6-Phosphonoglucono-D-lactone |
| SMILES | O=P(O)(O)OC[C@@H]1[C@H]([C@@H]([C@H](C(O1)=O)O)O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.