Fig. 1 · Structure
Documents & Downloads
6-T-GDP
Azathioprine Metabolite
6-T-GDP (6-Thioguanosine 5'-diphosphate) operates as a metabolite of azathioprine, targeted for its role in modulating inflammatory responses. By inhibiting Rac1 activity, 6-T-GDP reduces the transcription of inflammatory factors and decreases the expression of cell adhesion molecules. This action subsequently inhibits leukocyte migration and the onset of tissue inflammation, making it a valuable reagent for research into inflammatory diseases and mechanisms of immune regulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 16541-19-8 |
| Applications | Azathioprine Metabolite |
| Formula | C10H15N5O10P2S |
| Molecular Weight | 459.27 |
| Synonyms | 6-Thioguanosine 5'-diphosphate |
| SMILES | O[C@@H]1[C@H](O)[C@@H](COP(OP(O)(O)=O)(O)=O)O[C@H]1N(C=N2)C3=C2C(NC(N)=N3)=S |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.