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Biological Activity
6-?Thioinosine (6TI) is a purine antimetabolite, acts as an anti-adipogenesis agent, downregulates mRNA levels of PPAR γ and C/EBPα, as well as PPAR γ target protein such as LPL, CD36, aP2, and LXRα.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 35.18 mL | 175.88 mL | 351.75 mL |
| 0.5 mM | 7.04 mL | 35.18 mL | 70.35 mL |
| 1 mM | 3.52 mL | 17.59 mL | 35.18 mL |
| 5 mM | 0.7 mL | 3.52 mL | 7.04 mL |
*The above data is based on the productmolecular weight 284.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18412 |
|---|---|
| CAS No. | 574-25-4 |
| Formula | C10H12N4O4S |
| M. Wt | 284.29 |
| Purity | >98% |
| Synonyms | 6TI; 6-Mercaptopurine riboside |
| SMILES | S=C1NC=NC2=C1N=CN2C3[[email protected]@H]([[email protected]@H]([[email protected]@H](CO)O3)O)O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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