Fig. 1 · Structure
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653-47
666-15 Enhancer
653-47 is a potentiator that enhances the inhibitory activity of the cAMP-response element binding protein (CREB) induced by 666-15. Although it exhibits a weak inhibition of CREB with an IC50 value of 26.3 μM, its primary function is as an enhancer. This compound is utilized in research focused on CREB-related signaling pathways and the modulation of gene expression in cellular models.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 1224678-75-4 |
| Applications | 666-15 Enhancer |
| Formula | C20H19ClN2O3 |
| Molecular Weight | 370.83 |
| SMILES | O=C(C1=C(OCCCN)C=C2C=CC=CC2=C1)NC3=CC=C(Cl)C=C3O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.