Fig. 1 · Structure
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680C91
TDO Inhibitor
680C91 is a selective inhibitor of tryptophan 2,3-dioxygenase (TDO), exhibiting a potent Ki of 51 nM. By targeting TDO, a crucial enzyme in tryptophan catabolism, 680C91 plays a significant role in modulating tryptophan metabolism. This reagent is particularly valuable in the exploration of cancer immunotherapy and Alzheimer’s disease research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 163239-22-3 |
| Applications | TDO Inhibitor |
| Formula | C15H11FN2 |
| Molecular Weight | 238.26 |
| SMILES | FC1=CC2=C(C=C1)C(/C=C/C3=CC=CN=C3)=CN2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.