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6β-Hydroxy-7α-thiomethylspirolactone

Spironolactone Metabolite

6β-Hydroxy-7α-thiomethylspirolactone is a metabolite of the antihypertensive agent spironolactone, primarily targeting mineralocorticoid receptors. This compound exhibits key biological activity in the modulation of electrolyte balance and fluid retention, making it relevant for research into cirrhotic ascites. Its role in understanding spironolactone's pharmacodynamics enhances its utility in pharmacological studies and metabolic research.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	42219-60-3
Applications	Spironolactone Metabolite
Formula	C₂₃H₃₂O₄S
Molecular Weight	404.56
SMILES	C[C@@]12[C@@]3(OC(CC3)=O)CC[C@@]1([H])[C@@]4([H])[C@]([C@@]5(C([C@@H]([C@H]4SC)O)=CC(CC5)=O)C)([H])CC2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.