Fig. 1 · Structure
Documents & Downloads
6PGD-IN-1
6PGD Inhibitor
6PGD-IN-1 is a specific inhibitor of 6-phosphogluconate dehydrogenase (6PGD), offering an IC50 value of 17.8 μM and a Kd of 17.1 μM. This compound exhibits notable antitumor activity, making it a valuable tool for research into cancer metabolism and potential therapeutic strategies targeting the pentose phosphate pathway. Its ability to modulate 6PGD activity provides opportunities for exploring its role in cellular proliferation and survival in cancer studies.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 5539-66-2 |
| Applications | 6PGD Inhibitor |
| Formula | C15H10O4 |
| Molecular Weight | 254.24 |
| Synonyms | 1-Hydroxy-8-methoxyanthraquinone |
| SMILES | O=C1C2=C(C=CC=C2OC)C(C3=CC=CC(O)=C13)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.