Fig. 1 · Structure
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(6R)-Leucovorin
Derivative of Folic Acid
(6R)-Leucovorin is a derivative of folic acid that acts primarily as a cofactor in enzymatic reactions involving folate metabolism. This compound is essential for DNA synthesis, repair, and methylation, highlighting its importance in cellular processes. It is widely used in research applications related to cancer therapy, hematology, and the study of folate-related disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 73951-54-9 |
| Applications | Derivative of Folic Acid |
| Formula | C20H23N7O7 |
| Molecular Weight | 473.44 |
| Synonyms | (6R)-Folinic acid |
| SMILES | O=C(CC[C@H](NC(C1=CC=C(C=C1)NC[C@H]2N(C3=C(NC2)NC(N)=NC3=O)C=O)=O)C(O)=O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.