Fig. 1 · Structure
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7-Desmethyl-agomelatine
Agomelatine Metabolite
7-Desmethyl-agomelatine is a primary metabolite of Agomelatine, functioning as a selective agonist at melatonin receptors MT1 and MT2, while serving as an antagonist of the 5-HT2C receptor. This compound is of significant interest in research focused on the modulation of circadian rhythms and the treatment of mood disorders. Its unique pharmacological profile makes it a valuable tool for studies exploring the interplay between melatonin signaling and serotonin pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 152302-45-9 |
| Applications | Agomelatine Metabolite |
| Formula | C14H15NO2 |
| Molecular Weight | 229.28 |
| SMILES | CC(NCCC1=C2C=C(O)C=CC2=CC=C1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.