Fig. 1 · Structure

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7-F-4-I-Desamino lenalidomide

Ligand for E3 Ligase

7-F-4-I-Desamino lenalidomide acts as a ligand for the E3 ubiquitin ligase cereblon (CRBN). This compound facilitates the recruitment of cereblon to target proteins, enabling the development of proteolysis-targeting chimeras (PROTACs). It is a valuable tool for research in targeted protein degradation and the study of protein interactions within cellular pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 2207569-51-3
Applications Ligand for E3 Ligase
Formula C13H10FIN2O3
Molecular Weight 388.14
SMILES
O=C1NC(=O)C(N2C(=O)C=3C(F)=CC=C(I)C3C2)CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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