7-Hydroxy Granisetron-d3

Catalog No.: B14023
Stable Isotope
7-Hydroxy Granisetron-d3 is a deuterium-labeled derivative of 7-Hydroxy Granisetron, a potent 5-HT3 receptor antagonist. This stable isotope is employed in pharmacokinetic studies and metabolic research to trace the metabolic pathways and disposition of granisetron in biological systems, providing insightful data for drug development and efficacy evaluation. Its unique isotopic labeling enhances quantitative analysis in mass spectrometry applications.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description7-Hydroxy Granisetron-d3 is a deuterium-labeled derivative of 7-Hydroxy Granisetron, a potent 5-HT3 receptor antagonist. This stable isotope is employed in pharmacokinetic studies and metabolic research to trace the metabolic pathways and disposition of granisetron in biological systems, providing insightful data for drug development and efficacy evaluation. Its unique isotopic labeling enhances quantitative analysis in mass spectrometry applications.
Product Information
Catalog NumB14023
FormulaC18H21D3N4O2
Molecular Weight331.43
CAS Number2124272-02-0
SMILESCN([C@@H](CCC1)C2)[C@H]1C[C@@H]2NC(C(C3=CC=C4)=NN(C([2H])([2H])[2H])C3=C4O)=O
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