7-Hydroxy ropinirole bromide

Catalog No.: A60200
DA2 Receptor Agonist
7-Hydroxy ropinirole bromide is a selective DA2 receptor agonist that demonstrates significant inhibitory effects on neurotransmitter release and sympathetic nerve responses. This compound, a derivative of N,N-di-n-propyldopamine (DPDA), has shown promise in isolated perfused rabbit ear artery models, making it a valuable tool for studying cardiovascular and neurological disorders. Its targeted mechanism of action underscores its relevance in exploring therapeutic interventions in these fields.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description7-Hydroxy ropinirole bromide is a selective DA2 receptor agonist that demonstrates significant inhibitory effects on neurotransmitter release and sympathetic nerve responses. This compound, a derivative of N,N-di-n-propyldopamine (DPDA), has shown promise in isolated perfused rabbit ear artery models, making it a valuable tool for studying cardiovascular and neurological disorders. Its targeted mechanism of action underscores its relevance in exploring therapeutic interventions in these fields.
Product Information
Catalog NumA60200
FormulaC16H25BrN2O2
Molecular Weight357.29
CAS Number81654-57-1
SMILESO=C1NC2=C(C1)C(CCN(CCC)CCC)=CC=C2O.Br
SynonymsSK&F 89124 bromide
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