Fig. 1 · Structure
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7-Hydroxyquetiapine
Quetiapine Metabolite
7-Hydroxyquetiapine is the primary active metabolite of the antipsychotic agent Quetiapine. It functions by modulating various neurotransmitter systems, particularly serotonin and dopamine receptors, contributing to its therapeutic effects in managing psychiatric disorders. This compound is valuable for studying the pharmacological profile of Quetiapine and investigating its metabolic pathways in both in vitro and in vivo research settings.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 139079-39-3 |
| Applications | Quetiapine Metabolite |
| Formula | C21H25N3O3S |
| Molecular Weight | 399.51 |
| Synonyms | ICI 214227 |
| SMILES | OC1=CC=C2C(SC3=CC=CC=C3C(N4CCN(CCOCCO)CC4)=N2)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.