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7-MAD-MDCPT-AC-(s-cyclopropane)

Camptothecin Derivative

7-MAD-MDCPT-AC-(s-cyclopropane) is a camptothecin derivative that functions as a cytotoxic agent targeting topoisomerase I. This compound can be conjugated to monoclonal antibodies through linkers to create antibody-drug conjugates (ADCs) aimed at enhancing targeted delivery of anti-cancer therapies. Its applications are particularly relevant in cancer research, where it aids in the study of therapeutic mechanisms and potential efficacy in tumor treatment.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2911575-71-6
Applications	Camptothecin Derivative
Formula	C₂₇H₂₅N₃O₈
Molecular Weight	519.50
SMILES	O[C@@H](C1CC1)C(NCC2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=O)=NC6=CC(OCO7)=C7C=C62)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.