Fig. 1 · Structure
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7-Methyl-6-mercaptopurine
TPMT Substrate
7-Methyl-6-mercaptopurine is a purine derivative that serves as a substrate for thiopurine methyltransferase (TPMT). It exhibits Km and Vmax values of 231 μM and 2340 U/mg protein, respectively, making it relevant for studies involving TPMT enzymatic activity. This compound is utilized in research applications focused on drug metabolism and biomarker discovery in thiopurine therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Substrate |
| CAS Number | 3324-79-6 |
| Applications | TPMT Substrate |
| Formula | C6H6N4S |
| Molecular Weight | 166.20 |
| SMILES | S=C1NC=NC2=C1N(C)C=N2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.