Fig. 1 · Structure
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7-Methylcoumarin
Coumarin
7-Methylcoumarin is a coumarin derivative that functions as a mechanism-based inhibitor of CYP2A6. It exhibits significant hepatoprotective and antioxidant activities, effectively reducing serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), and total bilirubin in rat models of CCl4-induced liver injury. Additionally, 7-Methylcoumarin restores serum levels of total protein and albumin while mitigating oxidative stress. This compound also demonstrates the ability to decrease mitotic activity in A. sativum promeristem, making it valuable for various biological research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2445-83-2 |
| Applications | Coumarin |
| Formula | C10H8O2 |
| Molecular Weight | 160.17 |
| SMILES | O=C1C=CC2=CC=C(C)C=C2O1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.