Fig. 1 · Structure
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7-Nitroindole
Base Analog
7-Nitroindole is a cleavable base analog that serves as a photochemical precursor for the generation of 2'-deoxyribonolactone oxidative damage sites in DNA strands. This reagent is particularly useful for researching photo-controlled DNA breakage mechanisms and studying the effects of oxidative damage on nucleic acid structures. Its application in nucleic acid research provides insights into DNA repair processes and the impact of photochemical reactions on genetic material.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 6960-42-5 |
| Applications | Base Analog |
| Formula | C8H6N2O2 |
| Molecular Weight | 162.15 |
| SMILES | O=[N+](C1=CC=CC2=C1NC=C2)[O-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.