Fig. 1 · Structure
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7-TFA-ap-7-Deaza-dG
Modified Nucleoside
7-TFA-ap-7-Deaza-dG is a modified nucleoside designed for use in nucleic acid synthesis. This compound features an alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc), a pivotal click chemistry reaction. Its unique properties make it valuable for creating labeled oligonucleotides and studying RNA/DNA interactions, facilitating advancements in genetic research and molecular biology applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 666847-77-4 |
| Applications | Modified Nucleoside |
| Formula | C16H16F3N5O5 |
| Molecular Weight | 415.32 |
| SMILES | OC[C@@H]1[C@@H](O)C[C@H](N2C(N=C(N)NC3=O)=C3C(C#CCNC(C(F)(F)F)=O)=C2)O1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.