Fig. 1 · Structure
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7α,27-Dihydroxycholesterol
7α,27-Dihydroxycholesterol is an oxysterol that serves as a metabolite of 27-Hydroxycholesterol (27-OHC) and possesses oxidized side chains. This compound is significant in lipidomic studies related to various pathological conditions, including neurological diseases, obesity metabolic syndrome, Smith-Lemli-Opitz syndrome, and diabetes. Additionally, 7α,27-Dihydroxycholesterol functions as a ligand for Epstein-Barr virus-induced gene 2 (EBI2), and its levels are known to decrease following lipopolysaccharide activation. Furthermore, it is structurally related to 7α,25-dihydroxycholesterol (7α25-OHC).
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 4725-24-0 |
| Formula | C27H46O3 |
| Molecular Weight | 418.65 |
| SMILES | C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C)CO)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H](CC4)O)=C[C@H]3O)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.