Fig. 1 · Structure

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7α-(Thiomethyl)spironolactone

Nuclear Steroid Receptor Antagonist

7α-(Thiomethyl)spironolactone is a nuclear steroid receptor antagonist that inhibits the activity of steroid hormone receptors. This compound exhibits significant biological activity by modulating receptor signaling pathways, making it a valuable tool in the study of endocrine functions and related disorders. Additionally, it has potential applications in coronavirus research, contributing to the understanding of viral pathogenesis and therapeutic strategies.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 38753-77-4
Applications Nuclear Steroid Receptor Antagonist
Formula C23H32O3S
Molecular Weight 388.56
Synonyms 7α-Thiomethylspironolactone
SMILES
C[C@@]12[C@@]3(OC(CC3)=O)CC[C@@]1([H])[C@@]4([H])[C@]([C@@]5(C(C[C@H]4SC)=CC(CC5)=O)C)([H])CC2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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