Fig. 1 · Structure
Documents & Downloads
7DG
PKR Inhibitor
7DG (7-Desacetoxy-6,7-dehydrogedunin) is a selective inhibitor of protein kinase R (PKR). It is known for its ability to shield macrophages from pyroptosis induced by lethal toxins, thereby playing a crucial role in cell survival during inflammatory responses. This compound is valuable for research focused on understanding immune pathways and studying the mechanisms of cell death.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 26927-01-5 |
| Applications | PKR Inhibitor |
| Formula | C26H30O5 |
| Molecular Weight | 422.51 |
| Synonyms | 7-Desacetoxy-6,7-dehydrogedunin |
| SMILES | O=C1O[C@@H](C2=COC=C2)[C@]3(C)CC[C@@]4([H])[C@](C=C[C@@]5([H])C(C)(C)C(C=C[C@@]54C)=O)(C)[C@@]36[C@@H]1O6 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.