(7R)-Elisrasib

Catalog No.: A63569
KRASG12C Inhibitor
(7R)-Elisrasib is a selective inhibitor targeting the KRASG12C mutation, a key driver in various cancers. This compound demonstrates potent antitumor activity, effectively inhibiting tumor growth in preclinical mouse models. It is primarily used in cancer research focused on KRAS-driven tumors and aids in the investigation of targeted therapies for oncogenic mutations.
Grouped product items
Size Price Stock Qty
1mg
$360.00
In stock
5mg
$900.00
In stock
10mg
$1,480.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(7R)-Elisrasib is a selective inhibitor targeting the KRASG12C mutation, a key driver in various cancers. This compound demonstrates potent antitumor activity, effectively inhibiting tumor growth in preclinical mouse models. It is primarily used in cancer research focused on KRAS-driven tumors and aids in the investigation of targeted therapies for oncogenic mutations.
Product Information
Catalog NumA63569
FormulaC32H35F6N7O3
Molecular Weight679.66
CAS Number2706637-12-7
SMILESFC(F)(F)C(C(C)=CC(N)=C1F)=C1[C@H]2CC3=NC(OC[C@@]45N(CCC5)C[C@@H](C4)F)=NC(N6C[C@@H](N(CC6)C(C(F)=C)=O)CC#N)=C3CO2
Synonyms(7R)-D3S-001
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2