Fig. 1 · Structure
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(±)8(9)-EpETE
Epoxide
(±)8(9)-EpETE is an epoxide derived from eicosapentaenoic acid (EPA) through the action of various cytochrome P450 isoforms. This compound is known for its ability to relax vascular and airway smooth muscle by activating large conductance Ca2+-activated K+ (BKCa) channels via direct interaction with BKα subunits. (±)8(9)-EpETE serves as a valuable tool in research applications focusing on vascular function, smooth muscle physiology, and the physiological roles of eicosanoids in inflammation and signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 851378-93-3 |
| Applications | Epoxide |
| Formula | C20H30O3 |
| Molecular Weight | 318.45 |
| Synonyms | (±)8,9-EEQ; (±)8,9-epoxy Eicosatetraenoic acid |
| SMILES | CC/C=C\C/C=C\C/C=C\CC1C(C/C=C\CCCC(O)=O)O1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.