Fig. 1 · Structure
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8-Aminoadenosine
ATP Levels Reducer
8-Aminoadenosine is a nucleoside analogue that primarily reduces intracellular ATP levels, leading to the inhibition of mRNA synthesis. This compound effectively disrupts the Akt/mTOR signaling pathway, promoting autophagy and apoptosis through a mechanism that is independent of p53. Due to its ability to combat cellular energy metabolism and promote programmed cell death, 8-Aminoadenosine is of particular interest in anti-tumor research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 3868-33-5 |
| Applications | ATP Levels Reducer |
| Formula | C10H14N6O4 |
| Molecular Weight | 282.26 |
| Synonyms | 8-NH2-Ado |
| SMILES | O[C@H]1[C@@H](O)[C@H](N2C(N=CN=C3N)=C3N=C2N)O[C@@H]1CO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.