8-Bromo-octanoic acid 2,5-dioxo-pyrrolidin-1-yl ester

Catalog No.: A94540
Biochemical Assay Reagent
8-Bromo-octanoic acid 2,5-dioxo-pyrrolidin-1-yl ester functions as a biochemical assay reagent with a terminal bromide and an N-hydroxysuccinimide (NHS) ester. The bromide serves as an excellent leaving group for nucleophilic substitution reactions, enabling efficient modification of various biomolecules. The NHS ester facilitates the labeling of primary amines in proteins, amine-modified oligonucleotides, and other amine-containing compounds, making it a valuable tool for research applications in bioconjugation and chemical biology.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
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Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
Description8-Bromo-octanoic acid 2,5-dioxo-pyrrolidin-1-yl ester functions as a biochemical assay reagent with a terminal bromide and an N-hydroxysuccinimide (NHS) ester. The bromide serves as an excellent leaving group for nucleophilic substitution reactions, enabling efficient modification of various biomolecules. The NHS ester facilitates the labeling of primary amines in proteins, amine-modified oligonucleotides, and other amine-containing compounds, making it a valuable tool for research applications in bioconjugation and chemical biology.
Product Information
Catalog NumA94540
FormulaC12H18BrNO4
Molecular Weight320.18
CAS Number1155387-35-1
SMILESO=C(CCCCCCCBr)ON1C(CCC1=O)=O
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