Fig. 1 · Structure
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8-Bromoadenine
DNA Radiosensitizer
8-Bromoadenine is a DNA radiosensitizer that functions by inhibiting the repair of DNA single-strand breaks within cells. As a brominated derivative of adenine, it is utilized in research to study the mechanisms of radiosensitivity in cancer therapy. Additionally, its structure allows for the synthesis of deuterated adenine, expanding its applications in molecular biology and biochemistry research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 6974-78-3 |
| Applications | DNA Radiosensitizer |
| Formula | C5H4BrN5 |
| Molecular Weight | 214.02 |
| Synonyms | 8-Bromo-9H-purin-6-amine |
| SMILES | BrC1=NC2=C(N1)C(N)=NC=N2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.