Fig. 1 · Structure
Documents & Downloads
8-Cyclopentyl-1,3-dimethylxanthine
A1 Receptor Antagonist
8-Cyclopentyl-1,3-dimethylxanthine is a selective antagonist of the adenosine A1 receptor, exhibiting a binding affinity (Ki) of 10.9 nM for the A1 receptor, while demonstrating significantly lower affinity of 1440 nM for the A2 receptor. This compound is valuable for research applications aimed at studying the role of A1 receptor signaling in various physiological and pathological processes, including cardiovascular function and neuroprotection. Additionally, its selectivity makes it a useful tool in exploring the therapeutic potential of adenosine modulation.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 35873-49-5 |
| Applications | A1 Receptor Antagonist |
| Formula | C12H16N4O2 |
| Molecular Weight | 248.28 |
| SMILES | O=C(N1C)N(C)C2=C(N=C(C3CCCC3)N2)C1=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.