Fig. 1 · Structure

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8 Hydroxy PIPAT oxalate

5-HT Receptor Agonist

8 Hydroxy PIPAT oxalate is a selective agonist of the 5-HT1A receptor. This compound activates serotonergic signaling pathways, promoting the degranulation of enteric mast cells and enhancing spontaneous histamine release in both guinea pig and human intestinal preparations. Its ability to modulate histamine release suggests potential applications in understanding and addressing functional gastrointestinal disorders, including irritable bowel syndrome.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 1451210-48-2
Applications 5-HT Receptor Agonist
Formula C18H24INO5
Molecular Weight 461.29
SMILES
OC(C(O)=O)=O.OC1=C2C(CCC(C2)N(CCC)C/C=C/I)=CC=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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