Fig. 1 · Structure

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8-Hydroxyamoxapine

Antidepressant

8-Hydroxyamoxapine is an orally active antidepressant that primarily functions as a norepinephrine and serotonin reuptake inhibitor. By blocking the reuptake of these neurotransmitters at synaptic sites, it enhances their availability, contributing to improved mood and emotional regulation. This compound is useful in research exploring the mechanisms underlying depression and the development of novel therapeutic agents for mood disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 61443-78-5
Applications Antidepressant
Formula C17H16ClN3O2
Molecular Weight 329.78
Synonyms 8-OHAMX
SMILES
OC1=CC=C2OC3=CC=C(Cl)C=C3C(N4CCNCC4)=NC2=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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