Fig. 1 · Structure
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8-iso Prostaglandin F1β
Vasoconstrictor
8-iso Prostaglandin F1β is an isoprostane that primarily targets the thromboxane A2 (TXA2) receptor to induce vasoconstriction. This compound demonstrates significant contractile efficacy in neonatal porcine pulmonary arteries, pulmonary veins, and mesenteric arteries, and is influenced by the activity of tyrosine kinase and Rho kinase. It is a valuable tool for research into vascular biology and the mechanisms of vasoconstriction.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 26771-95-9 |
| Applications | Vasoconstrictor |
| Formula | C20H36O5 |
| Molecular Weight | 356.50 |
| SMILES | CCCCC[C@H](O)/C=C/[C@@H]1[C@@H]([C@H](O)C[C@H]1O)CCCCCCC(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.